Should doctors bend the rules of a study so that a patient can receive an experimental drug? What if the rule bending contaminates the data, and a potentially lifesaving drug is never approved?
In today’s Doctor and Patient column, Dr. Pauline W. Chen writes about a challenge faced by doctors conducting clinical trials. Do they focus on the needs of the study or the needs of the patient? She writes:
As collaborators in research, they want to obtain information that is valid and able to be generalized for all future patients; but as doctors working within a patient-doctor relationship, they need to focus only on improving the condition of the patient before them. A patient in a chemotherapy clinical trial, for example, might complain of severe nausea after receiving a dose of an experimental drug. While the doctor as researcher might place a high priority on limiting the types of antinausea medications because of fears they could interact with and affect the experimental drug’s effects, that same doctor as patient advocate might choose to ignore the list of “approved” antinausea medications in order to use one that has previously worked.
To learn more, including the moving story of a woman who wanted to extend her life for just a few months so she could meet her grandchild, read the full column, “Bending the Rules of Clinical Trials.” Then please join the discussion below.
Here is my stance on the issue as say;
By Dr RazaHaider
“Bending the Rules of Clinical Trials”
Doctor! Can I have few more breath to see my legitimate arrivals as sons, daughters or grand children?
“No! I am sorry; since you don’t qualify; for, our strict criteria to award a trial to replenish few more breathe to you and similar siblings as future to come; this is as been designed by FDA and institutional review board and similar authorities as counsel of people in terms of “common rule”, which strictly awards mercenary death over dying desire.
We have strict compliance as initialization; before we can award life to humanity.
Your desire for a little more life has no value; over our prerogative orders as compulsion and obligation to follow designed rules and regulations.
Hence; I feel sorry; thus secluding inspite; my instinct to award you breathe in lieu of orders in the name of ethics, to halt my expertise and skill.”
What is this concept to let someone die within grilled concepts of rules and regulation?
What is this irrationalism in the name of ethics and checks that compulsively allow death to take its revenge from life inspite that; something can be done voluntarily, to reach and response as palatable destinations of desire as quantum of life?
I must have a valid reason to be acquainted with this term “Written Inform consent” and its physical value in which, a patient put himself over the counter of belief that ‘from now and onward his mind and soul shall believe ultimate resultant ; through the skill and expertise of a physician.
No logic and law can and shall curtail and debar request as plea as in this case few breathe; by formulating rules as special corset of ethics and criteria of selection.
This is a stubborn and unprecedented attitude of few mongers of ethics and rationalism who are willfully; I say it, criminally subjecting individual to death as calculated fate without striving to hold death by assertion as trial.
Defining subject objective rules of clinical trials in its role model is a separate verse but special circumstances like this one can not legitimately be own since; this is a circumstantial unconditional event and involves the plea of a dying soul, which by any means of honor, must be kept above.
In my opinion; its here where these universal policeman’s as “ethicist” and “counsel rule” should involve in humanly manner to certify the desire of patient hence selectively achieving wish at any cost without obligatory rules or especial incentive based policy to the sufferer thereof to remedy the dying as aid.
In my opinion bending the rules of clinical trial is as much the same obligatory duty of all concerned, who takes the responsibility; to deliver safe and secure debut of drug prior to end user and no chance whatsoever should go in vain or unattended if an iota of achievement is a hope.
Posted by: razahaider on: October 10, 2009
Democracy …………..is nothing more than a cumulative assertion of cumulative ignorance that award reign and region to individual wisdom whose understanding is bit above cumulative wisdom of awardees.
This is a cumulative power of ignorance to sublimate as per their ignorant perception; the power to rule and reinforce hence to ultimately prefix or suffix this phrase ignorant, hence excelling ignorance.
This is a power of individual as prerogative to choose some one from them or from surround; that is being visualize by people as more adversary in understanding and wisdom.
This is a highly obnoxious illogical procedure as selection that confers and transfer power by way of authority of cumulative ignorance hence; selecting a person that is perceivably fit in the eyes of ignorant.
In my opinion rules and reigns are the subject of intellect and are always transferred as transformation, from one intellectual to other therefore to manage means and manners hence; procure intellect for the ignorant, you may call wisdom.
Democracy is a real menace especially for the society where ignorance supervenes; and hazards due to this selection are always fearsome as we see in countries like Pakistan.
Psychiatry and behavioral science are unique subjects; which drag almost every concept of human attitude as action, quality as trait and response as deviation, within its premises, therefore to create its different entity as specialty.
In a closed vicinity and funnel of psychiatrical diagnosis almost all individuals are perceived and evaluated as per define criteria of books as curriculum and any one escaping thus falling within the premises and counter; is tagged and diagnosed in the vicinity as anomaly or abnormality.
In psychiatrical analysis almost every person has some derangement if one genuinely looks in to the definition and domain of the terminology being practiced by these psychiatrists.
Although, genuinely; derangement as disease, is always associated with organic affiliation of system may it be visceral or hormonal, but nevertheless; and on the other end; emotional expectancy as suspicion; is also a chapter of verse in outskirt of such specialty.
Since criteria for such disease isolation as tendency ; is predefined as subject in books of psychiatry; smarts individuals who are absconders, politically confiscated, high profile jailed criminals, spies, military persons for ultimate discharge from service and many having reach and reassurance from the specialty as specialist ; settle their account of escape and beneficial discharge by utilizing the same defined pre domain of symptoms with the help of psychiatrist or perhaps physician.
This is to get relief and release with benefited discharge; hence escapes as run away with define fate through presented plate full of psychiatry.
This is a highly obnoxious undermined irrational practice as curse of this silent specialty allover the world, particularly in third world.
Posted by: razahaider on: October 6, 2009
“I never wanted to make your platform a battle field of deadlocks and death.
My escape must not be taken as overcoming.
I am very much there to move armored on even sight as call; so to offer my deterrence for you.
But still! My mind prohibits refraining a bit as retaliation; till its call of the nature and life.
So let them enjoy the way they like since they have my desire till its time to perish.
For you! You must associate within the depth of mind that people who stand by as stand buyers have their own norms in fight as retaliators.
“You got to flow with the wavelength of the wave since;
Rational fighters, lines up rows; as per, expected formulary of attack.
I may not indulge you as first line of defense but you must know,
Exposure is as equivalent as qualification.
You got to make your self up to the mark of expectation as comrade since;
Visionaries never leave their land and visions unattended hence;
Prepares generation to act and revolt for their own generation and as heirs; for soon to come generation and thereafter; as heritage.
Posted by: razahaider on: October 4, 2009
“How come, few among us, start thinking in our own way hence; perceiving same thing in different manner as thought?
Why is it that that people as majority understands things in same contest as understanding but few; floats ideas that are understandable to only little?
How come little ideas becomes the means of change where as; cumulative assertion as law becomes a fail portfolio?
In my opinion we are born alike, groom in similar fashion but are developed in different way as exposure.
Why this development takes its own course in different individuals; is a variant subject that resides in one’s environment as exposure?
You may say;
Some are being taught to get art where as; few are born artistic.
Some have silver spoon where as; many are the king of clay.
Truth is! It’s the nature that shines within your soul if you are near to its reality where as; making your environment in terms of nature or you may say; same as nature; never procure resultant results.” (Dr Raza)
Posted by: razahaider on: October 1, 2009
“We must abstain and refrain from such unfaithful acts; that puts a follower in to similar sibling as ‘Satin’.
Disobediences embarrass the verdict of Almighty to claim human as (His) (SWT) most compliant and valued creation as messenger.
How can we justify such ill moral acts that are believably being seen, duly watched and recorded by the Lord of the universe (SWT) and every existing creature around (Him) (SWT) and human; during the course of its action as performance?
I believe; being a logical evaluator; it is for sure that these humanly acts as wrongful deeds and ill moral practices as exhibitions and doings, are more than a refuted and rebutted assertion of Satin’ and his empowering fleet of supporters.
‘Satin’ negated the concept by not bowing his head for the creation thus; eventually recalled to verify his act as dominant; but actually he contested the concept of almighty at (His) (SWT)) selection thus putting; his initial disobedience as say; in terms of unpardoned sin.
Where as; these acts of unfaithfulness and disregards by humans especially Muslim; after the challenging notion as request of ‘Satin” to spare and allow him ,so to defang and deviate humanity; again puts ‘satin’ in affirmative claim to make his position understandable thereby making his claim more assenting and thereof embarrassing.”(Dr Raza)
Recent Comments